WVU Cranial Base Neurosurgery The Cranial Base Surgery Center at West Virginia University specializes in treating complex medical conditions involving lesions at the base of the skull. These include tumors, congenital anomalies, and infectious or inflammatory conditions. Because of the many important structures located in this area, cranial base lesions have long been some of the most difficult challenges for neurosurgeons and their patients. Our surgeons are skilled in the most advanced techniques and the latest technologies, and we can offer help for conditions that previously may have been considered untreatable.